ISSN: 2041-6792

Clinical Investigation

Stem Cell Transplantation Review Articles

 A somatic cell transplant, also called a bone marrow transplant, are often wont to treat certain sorts of cancer. This procedure could be called peripheral somatic cell transplant or cord blood transplant, counting on where the stem cells come from. Here we’ll explain stem cells and stem cell transplant, cover some of the issues that come with transplants, and describe what it's like to donate stem cells A procedure in which a patient receives healthy stem cells to exchange their own stem cells that are destroyed by treatment with radiation or high doses of chemotherapy.  A stem cell transplant may be autologous , allogeneic, syngeneic, or cord blood Hematopoietic stem cell transplantation (HSCT) involves the intravenous (IV) infusion of autologous or allogeneic stem cells to reestablish hematopoietic function in patients whose bone marrow or system is broken or defective. Preparative or conditioning regimens involve delivery of maximally tolerated doses of multiple chemotherapeutic agents with nonoverlapping toxicities and should be classified as follows:   Myeloablative regimens – These are designed to kill all residual cancer cells in autologous or allogeneic transplantation and to cause immunosuppression for engraftment in allogeneic transplantation; they'll be further subclassified as radiation-containing or non–radiation-containing Nonmyeloablative regimens – These are immunosuppressive but not myeloablative and believe the graft-versus-tumor effect to kill tumor cells with donor T cells.  

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