RNA Sequencing Impact Factor
The RNA Impact factor may be a journal that gives rapid publication of serious original research altogether areas of RNA structure and performance in eukaryotic, prokaryotic, and viral systems. It covers a broad range of subjects in RNA research, including structural analysis by biochemical or biophysical means; mRNA structure, function, and biogenesis; alternative processing: cis-acting elements and trans-acting factors; ribosome structure and function; translational control; RNA catalysis; tRNA structure, function, biogenesis, and identity; RNA editing; rRNA structure, function, and biogenesis; RNA transport and localization; regulatory RNAs; large and little RNP structure, function and biogenesis; viral RNA metabolism; RNA stability and turnover; in vitro evolution; and RNA chemistry.In recent years, high-throughput next-generation
sequencing technology has allowed a rapid increase in diagnostic capacity and precision through different
bioinformatics processing algorithms, tools, and pipelines. The identification, annotation, and classification of sequence variants within different target regions are now considered a gold standard in clinical genetic diagnosis. However, this procedure lacks the power to link regulatory events like differential splicing to diseases. RNA-seq is important in clinical routine so as to interpret and detect among others splicing events and splicing variants, because it would increase the diagnostic rate by up to 10–35%. The transcriptome features a very dynamic nature, varying consistent with tissue type, cellular conditions, and
environmental factors which will affect regulatory events like splicing and therefore the expression of genes or their isoforms. RNA-seq offers a strong technical analysis of this complexity, but it requires a profound knowledge of computational/statistical tools which will got to be adjusted counting on the disease under study.
High Impact List of Articles
Relevant Topics in Clinical