ISSN: 1755-5310 (Electronic)1755-5302 (Print)

Interventional Cardiology

Rheumatoid Arthritis Peer-review

 Rheumatoid arthritis (RA) may be a long-term autoimmune disease that primarily affects joints. It typically leads to warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with an equivalent joints typically involved on each side of the body. The disease can also affect other parts of the body. This may end in a coffee red blood corpuscle count, inflammation round the lungs, and inflammation round the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months. While the explanation for atrophic arthritis isn't clear, it's believed to involve a mixture of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is formed totally on the idea of an individual's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases which will present similarly include systemic LE, rheumatoid arthritis, and fibromyalgia among others. The goals of treatment are to scale back pain, decrease inflammation, and improve an individual's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. Disease-modifying antirheumatic drugs (DMARDs), such as hydroxychloroquine and methotrexate, may be used to try to slow the progression of disease. Biological DMARDs could also be used when disease doesn't answer other treatments. However, they'll have a greater rate of adverse effects. Surgery to repair, replace, or fuse joints may help in certain situations. Most medicine treatments aren't supported by evidence.  

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