ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Retinoblastoma Innovations

Retinoblastoma is a rare type of eye cancer that typically develops before age 5 in early childhood. This form of cancer develops in the retina, which is the specialized light-sensitive tissue that detects light and color at the back of the eye. The illness often only affects one eye in children with retinoblastoma. However, one in three children with retinoblastoma in both eyes develops cancer. A visible whiteness in the pupil, called "cat 's eye reflex" or leukocoria, is the most common first sign of retinoblastoma. This unusual whiteness is particularly noticeable in dim light, or in a flash photograph. Other signs and symptoms of retinoblastoma include crossed eyes or eyes not pointing in the same direction (strabism), which may cause squinting; color change in the colored part of the eye (iris); redness, discomfort or swelling of the eyelids; and blindness or poor vision in the affected eye or eye. Retinoblastoma is often curable upon early diagnosis. This cancer, however, can spread beyond the eye to other parts of the body if it is not treated promptly. This advanced form of retinoblastoma can present life-threatening consequences.

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