ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Retinal Ischemia Peer-review Journals

 Retinal ischemia  is that the underlying pathophysiology in diabetic retinopathy, retinal vascular occlusive disease, and retinopathy of prematurity. If it's shown to be safe and effective, the OxyCell implant may have applications in retinal ischemic conditions. Decreased blood flow to the retina is that the underlying pathophysiology during a number of major retinal diseases, including diabetic retinopathy, retinal vascular occlusive disease, and retinopathy of prematurity. This tissue ischemia causes a cascade of cellular events, most notable among these the overproduction of VEGF, which causes neovascularization and increased vessel permeability. Current treatments for these diseases include laser, vitrectomy, and intravitreal anti-VEGF injections. Although these are all effective, they are doing not address the underlying pathophysiology: decreased tissue oxygen.  

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