ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Randomized Control Trials Articles

Randomized controlled trial (RCT) A study during which people are allocated randomly (by chance alone) to receive one among several clinical interventions. One of these interventions is that the standard of comparison or control. The control could also be a typical practice, a placebo ("sugar pill"), or no intervention in the least. Someone who takes part during a randomized controlled trial (RCT) is known as a participant or subject. RCTs seek to live and compare the outcomes after the participants receive the interventions. Because the outcomes are measured, RCTs are quantitative studies. In sum, RCTs are quantitative, comparative, controlled experiments during which investigators study two or more interventions during a series of people who receive them in random order. The RCT is one among the only and most powerful tools in clinical research. RCTs aim to seek out which treatment is best by making a good comparison between: •   a new treatment and an existing treatment •    two (or more) existing treatments •   a new treatment and no treatment, or a placebo (where there's no existing treatment) In an RCT, two or more groups of people are compared: one (or more) experimental group(s) who receive a replacement treatment, and an impact group, who receive the present standard treatment (which could be the simplest existing treatment, no treatment or a placebo).    

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