Stem Cell Research and Regenerative Medicine

Poly-nucleotide

 A polynucleotide molecule is a biopolymer consisting of 13 or more nucleotide monomers[1] that are covalently bound within a chain. Examples of polynucleotides with distinct biological function are DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). A polynucleotide strand is made of a sugar-phosphate backbone (such as a string in a strand of flags) and a variety of bases (such as flags), one per nucleotide. A polynucleotide is made when nucleotides are joined together by a polymerase enzyme. The strand has two distinct ends that we call 3 'and 5'.Polynucleotides consist of a long, unbranched chain with a backbone of sugar (ribose or deoxyribose) and units of phosphate with heterocyclic bases protruding regularly from the chain. The single-stranded form of the polynucleotides simplifies the study of DNA damage, though the aggregation of strands can be induced under certain pH conditions.

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