Pain Mechanism Scientific Journals
The most widely accepted and current definition of pain, established by the International Association for the Study of Pain (IASP), is "an unpleasant sensory and emotional experience related to acutal or potential tissue damage, or described in terms of tissue damage, or both." Although several theoretical frameworks are proposed to elucidate the physiological basis of pain, not one theory has been ready to exclusively incorporate everything of all the aspects of pain perception. The four most influential theories of pain
perception include Specificity, Intensity, Pattern AND circuit Control theories of pain. However, in 1968, Melzack and Casey described pain as multi-dimensional, where the sizes aren’t independent, but rather interactive. The dimensions include sensory-discriminative, affective-motivational and cognitive-evaluate components. Determining the foremost plausible pain mechanism(s) is crucial during clinical assessments as this will function a guide to work out the foremost appropriate treatment(s) for a patient. Therefore, criteria upon which clinicians may base their decisions for appropriate classifications have been established through an expert consensus-derived list of clinical indicators. The tables below were adapted from Smart et al. (2010) that classified pain mechanisms as 'nociceptive', 'peripheral neuropathic' and 'central' and outlined both subjective and objective clinical indicators for every . Therefore, these tables function an adjunct to any current knowledge and supply as an overview which will guide clinical
decision-making when determining the foremost appropriate mechanism(s) of pain.
High Impact List of Articles
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Dual bronchodilation for the treatment of chronic obstructive pulmonary disease: a review of the latest clinical data
Donald Banerji, Robert Fogel & Kai-Michael Beeh
Review: Clinical Trail Outcomes: Clinical Investigation
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Dual bronchodilation for the treatment of chronic obstructive pulmonary disease: a review of the latest clinical data
Donald Banerji, Robert Fogel & Kai-Michael Beeh
Review: Clinical Trail Outcomes: Clinical Investigation
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Non-inferiority designs and novel antimicrobials
Giorgio Tarchini
Editorial: Clinical Investigation
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Non-inferiority designs and novel antimicrobials
Giorgio Tarchini
Editorial: Clinical Investigation
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New treatment for Cushins disease given European Medicines Agency recommendation
News and Views: Clinical Investigation
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New treatment for Cushins disease given European Medicines Agency recommendation
News and Views: Clinical Investigation
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Current and emerging therapies for stroke prophylaxis in
atrial fibrillation
Eric TS Lim, Jonathan Yap, Chee Tang Chin
Review Article: Clinical Investigation
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Current and emerging therapies for stroke prophylaxis in
atrial fibrillation
Eric TS Lim, Jonathan Yap, Chee Tang Chin
Review Article: Clinical Investigation
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JAK2 inhibitors in the treatment of myeloproliferative neoplasms: rationale and clinical data
Raoul Tibes, Ruben Mesa
Review Article: Clinical Investigation
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JAK2 inhibitors in the treatment of myeloproliferative neoplasms: rationale and clinical data
Raoul Tibes, Ruben Mesa
Review Article: Clinical Investigation
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Lung cancer vaccines: a review of three ongoing trials
Sarah R Goodyear, Hossein Borghaei
Review Article: Clinical Investigation
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Lung cancer vaccines: a review of three ongoing trials
Sarah R Goodyear, Hossein Borghaei
Review Article: Clinical Investigation
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An approach to personalized medicine: the BATTLE trial
Niels Reinmuth & Michael Thomas
Review Article: Clinical Investigation
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An approach to personalized medicine: the BATTLE trial
Niels Reinmuth & Michael Thomas
Review Article: Clinical Investigation
Relevant Topics in Clinical