ISSN: 2044-9038 (Print) 2044-9046 (Electronic)

Clinical Practice

Open Access Pharmacogenomics Journals

 Journal of Pharmacogenomics & Pharmacoproteomics is an open access and peer reviewed journal includes a good range of field in its discipline to make a platform for the authors to make their valuable contributions towards the journal and therefore the referee process promises the publishing of quality, reliable and important articles for the readers and authors of scholarly, academic and scientific field. Journal of Pharmacogenomics & Pharmacoproteomics is an open access and peer reviewed journal includes a good range of field in its discipline to make a platform for the authors to make their valuable contributions towards the journal and therefore the referee process promises the publishing of quality, reliable and important articles for the readers and authors of scholarly, academic and scientific field. In cancer treatment, pharmacogenomics tests are wont to identify which patients are presumably to reply to certain cancer drugs. In behavioral health, pharmacogenomic tests provide tools for physicians and care givers to raised manage medication selection and side effect amelioration. Pharmacogenomics is additionally referred to as companion diagnostics, meaning tests being bundled with drugs. Examples include KRAS test with cetuximab and EGFR test with gefitinib. Beside efficacy, germline pharmacogenetics can help to spot patients likely to undergo severe toxicities when given cytotoxics showing impaired detoxification in relation with genetic polymorphism, like canonical 5-FU.In particular, genetic deregulations affecting genes coding for DPD, UGT1A1, TPMT, CDA and CYP2D6 are now considered as critical issues for patients treated with 5-FU/capecitabine, irinotecan, mercaptopurine/azathioprine, gemcitabine/capecitabine/AraC and tamoxifen, respectively.  

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