Multiple Myeloma Top Open Access Journals

Multiple myeloma is a cancer that develops in a type of plasma cell called a white blood cell. Plasma cells help you fight infections by producing germ recognizing and attacking antibodies. Multiple myeloma allows the cancer cells to build up in the bone marrow, where healthy blood cells are crowded out. Because of generating useful antibodies, the cancer cells produce abnormal proteins which can cause complications. Multiple myeloma treatment is not always necessary for people who have no signs or symptoms. A variety of options are available for people with multiple myeloma who need care, to help manage the disease. Doctors believe that myeloma starts in your bone marrow with one irregular plasma cell — the thick, blood-producing tissue that fills most of your bones in the centre. The abnormal cell is easy to multiply. Since cancer cells don't mature and then die like normal cells do, they grow and ultimately overpower healthy cell development. Myeloma cells grab healthy white blood cells and red blood cells in the bone marrow, leading to tiredness and an inability to combat infections. Myeloma cells tend to attempt to create antibodies, as healthy plasma cells do, but myeloma cells produce irregular antibodies that the body cannot use. Instead, abnormal antibodies build up in the body, causing problems including kidney damage. Cancer cells can also cause bone damage, which increases the risk of fractured bones. 

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