Marfan Syndrome High Impact Factor Journals

Marfan syndrome (MFS) may be a genetic disease that affects the animal tissue. Those with the condition tend to be tall and thin, with long arms, legs, fingers and toes. They also typically have flexible joints and scoliosis. The foremost serious complications involve the guts and aorta, with an increased risk of bicuspid valve prolapse and aneurysm . The lungs, eyes, bones, and therefore the covering of the medulla spinalis also are commonly affected. The severity of the symptoms of MFS is variable. MFS is caused by a mutation in FBN1, one among the genes that creates fibrillin, which ends up in abnormal animal tissue. It's an autosomal dominant disorder. About 75% of the time, the condition is inherited from a parent with the condition, while 25% of the time it's a replacement mutation. Diagnosis is usually supported the Ghent criteria. There is no known cure for MFS. Many of these with the disorder have a traditional anticipation with proper treatment. Management often includes the utilization of beta blockers like propranolol or atenolol or, if they're not tolerated, calcium channel blockers or ACE inhibitors. Surgery could also be required to repair the aorta or replace a heart valve. Avoiding strenuous exercise is suggested for those with the condition.      

High Impact List of Articles

Relevant Topics in