Induced Pluripotent Stem Cells Top Open Access Journals

IPSC are derived from skin or blood cells that are reprogrammed back to an embryonic-like pluripotent state that permits the event of a vast source of any sort of human cell needed for therapeutic purposes. For example, IPSC are often prodded into becoming beta islet cells to treat diabetes, blood cells to make new blood freed from cancer cells for a leukemia patient, or neurons to treat neurological disorders. In late 2007, a BSCRC team of college, Drs. Kathrin Plath, William Lowry, Amander Clark, and April Pyle were among the primary within the world to make human IPSC. At that point, science had long understood that tissue specific cells, like skin cells or blood cells, could only create other like cells. With this groundbreaking discovery, IPSC research has quickly become the inspiration for a replacement regenerative medicine. Using IPSC technology our faculty have reprogrammed skin cells into active motor neurons, egg and sperm precursors, liver cells, bone precursors, and blood cells. In addition, patients with untreatable diseases like, ALS, Rett Syndrome, Lesch-Nyhan Disease, and Duchesne’s dystrophy donate skin cells to BSCRC scientists for IPSC reprogramming research. The generous participation of patients and their families during this research enables BSCRC scientists to review these diseases within the laboratory within the hope of developing new treatment technologies.