Stem Cell Research and Regenerative Medicine

Induced Pluoripotent Stem Cells

Induced pluripotent stem cells (iPS cells), immature cells produced by mature cells (adults) and which regain the ability to differentiate into each type of cell in the body. Induced pluripotent stem cells (iPS cells) differ from embryonic stem cells (ES cells), which form cell mass in the embryo, but also pluripotent and ultimately produce all types of cells that make up the body. The first experiment was carried out with mouse cells. The following year iPS cells were obtained from human adult fibroblast cells. Until then, human stem cells can only be obtained from ancient human embryos by isolation. Therefore, an important feature of iPS cells is that they do not require embryos to be produced, their use has ethical issues. iPSC, which is produced by cells that are differentiated by genes that express too much temporarily which gives pluripotency, resembles embryonic stem cells in their potential and their proliferation capacity. The development of iPSC stimulates discussion of autologous cell therapy derived from iPSC, which will eliminate the need for ESC-derived cell products (allogeneic). The iPSC transplant does not require immunosuppression and has no ethical problems. 

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