Stem Cell Research and Regenerative Medicine

Genome-sequencing

Genome decoding refers to the sequencing of the whole genome of the organism. Many high-performance sequencing and database management methodologies have been applied. Primary genetic sequencing techniques include the clone-by-clone process and the entire genome shotgun chain. The clone-by-clone sequencing methodology performs well for larger genomes such as eukaryotic genomes, but produces a strong density genome outline. The whole genome shotgun (WGS) sequence does not require a genome map. The WGS approach is a quicker way of sequencing, but is not ideal for larger genomes such as eukaryotic genomes since they include a lot of repeated DNA sequences through which the assembly phase is difficult. Therefore, the advantages of both methods are used to speed up the genome sequencing process. 

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