ISSN: 2041-6792

Clinical Investigation

Developmental Toxicology Innovations

Developmental toxicology can be defined as the adverse changes in an organism during various stages of development including pre natal, post natal or during sexual development or maturation. Developmental toxicology usually interferes with the development of normal offspring. Innovations are new idea, device or process. Innovations are the application of better solutions that meet new requirements, inarticulate needs or existing market needs. It is proficient through more effective products, processes, services, technologies, or new ideas that are readily available to markets, governments and society. Innovations are something original and novel, as a significant, new that the market or society. This article is a report of the 8th Berlin Workshop on Developmental Toxicity held in May 2014. The main aim of the workshop was the continuing harmonization of terminology and innovations for methodologies used in the assessment of embryo- and fetotoxic findings. The following main topics were discussed: harmonized categorization of external, skeletal, visceral and materno-fetal findings into malformations, variations and grey zone anomalies, aspects of developmental anomalies in humans and laboratory animals, and innovations for new methodologies in developmental toxicology. The application of Version 2 terminology in the Dev Tox database was considered as a useful improvement in the categorization of developmental anomalies.    

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