Asthma Genetics Syndrome Research Articles

 Asthma  and allergy are common conditions with complex and heterogeneous etiologies.  Asthma and allergic disease often co-occur within the same individual or in several individuals within equivalent families. However, whether this co-occurrence reflects distinct conditions with shared pathogenic pathways or different clinical manifestations of an equivalent disease is currently unknown. Asthma  isn't one disease but rather an umbrella for multiple diseases with similar clinical features, and certain with different genetic and environmental contributors. On the one hand, more precise phenotypic definitions would allow identification of more homogeneous subgroups of patients with asthma and facilitate genetic studies. On other hand, the invention of asthma and allergy susceptibility loci could provide insights into phenotypic subgroups and ultimately inform the choice of targeted/effective treatment.