Anti-neutrophil Cytoplasmic Antibody

 Antibodies ar proteins that your system makes to fight foreign substances like viruses and bacterium. however ANCAs attack healthy cells referred to as neutrophils (a variety of white blood cell) by mistake. This will cause a disorder referred to as response inflammation. Response inflammation causes inflammation and swelling of the blood vessels. Anti-neutrophil cytoplasmic antibodies (ANCAs) are a group of autoantibodies, mainly of the type IgG, against antigens in neutrophil granulocyte cytoplasm (the most common type of white blood cell) and monocytes. In a number of autoimmune disorders, they are detected as a blood test but are especially associated with systemic vasculitis, called ANCA-associated vasculitides (AAVs). The way in which ANCA is developed is poorly understood although several hypotheses have been suggested. There is probably a genetic contribution, especially in genes that control immune response levels – although genetic susceptibility is likely to be linked to an environmental factor, some possible factors, including vaccination or silicate exposure.

High Impact List of Articles

Relevant Topics in