Study of Malignant Tumour Clinical Characteristics with Inflammatory ArthritisAuthor(s): Kim Gyun
Hematologic malignancy with cholangiocarcinoma (cHCC-CCA) is a rare primary liver cancer composed of differentiated cells of both hepatocytes and cholangiocytes. It is slightly more common in men and in Asian and Pacific islanders. Overall, the risk factors are similar to classical risk factors for hematologic malignancies. Taxonomies have evolved significantly over time. The latest WHO classification (2019) discards the previously accepted classification of cancers with stem cell characteristics and replaces the morphological diagnosis, primarily by routine staining, with the ability to distinguish between intermediate cancers. is emphasized. Assigned to subtypes and consider cholangiocarcinoma a subtype of cholangiocellular carcinoma. Immunohistochemical markers can be used for detailed identification but are of limited diagnostic value. Recent discoveries regarding the regulation of molecular signaling may provide new therapeutic approaches for this poor prognosis and difficult diagnosis.