Abstract

Sound implementation of human papillomavirus vaccination as a community-randomized trial

Author(s): M Lehtinen, KM French , J Dillner, J Paavonen & G Garnett

To be (most) effective, the very efficacious vaccines against oncogenic human papillomaviruses have to be implemented into national vaccination programs. Inferences from mathematical modeling studies can be made as to the most effective vaccination strategy in an ideal world. In addition, the best strategies can be evaluated against each other in community randomized trials. Results of such trials can hopefully guide vaccination implementation, which naturally varies owing to country-specific differences in economics, values (cultural and religious) and health policy