Role of clinician in therapeutic drug monitoring practice

Author(s): Mohammad Asif Saleem, Rabia Basharat, Nauman Anwer Rana and Saeed Akhtar Khan Khattak

Therapeutic drug monitoring is a clinical service in which to measuring different drugs in different time periods to manage a desired concentration of drugs in the patient’s blood. Clinicians approach the laboratory to monitor drug concentration to minimize toxicity and enhance therapeutic responses. The clinician manages the cases of a drug overdose and decides how to recoup drug toxicity with limited pharmaceutical requirements and figure out patient consent along with treatment. The main purpose of TDM is to use appropriate blood drug concentrations that possess a narrow therapeutic spectrum in order to optimize the clinical results. This review summarizes the key concept of therapeutic drug monitoring, its historical background, pharmacokinetic principles, the role of clinician and its future scope of TDM in clinical practice.