Pediatric patients undergoing interventional neuroradiology procedures' radiation dose and subsequent risk of developing brain tumors

Author(s): Henry Cristy

Dosimetric data from the Radiation Doses in Interventional Radiology Study for 49 pediatric patients who underwent neuroradiological procedures were used to calculate the average dose to the entire brain. Published algorithms based on data from A-bomb survivors were used to estimate the lifetime risk of developing radiation-related brain tumors. The size of the field and how the patient moves during the procedure can have a significant impact on how the dose is distributed within the brain. Organ-averaged brain dose was estimated to range from 6 to 1600 mGy, depending on the patient’s age and exposure conditions. Depending on the dose taken, age at exposure, and gender, the lifetime risk of being diagnosed with a brain tumor was estimated to be 3 to 40% higher than the normal background rate of 57 cases per 10,000. While critical vulnerabilities are related with these evaluations, we have measured the scope of conceivable portion and spread the vulnerability to determine a trustworthy scope of assessed lifetime risk for each subject. The best methods for reducing radiation dose and the risk of future tumor induction are collimation and limiting fluoroscopy time and dose rate.