Comparison of hemoglobin before and after modified ultrafiltration in pediatric cardiac surgery

Author(s): Muhammad Ali, Attiya Hameed Khan, Hammad Ahmed, Imtiaz Ali Bangash, Sajjad Ali Shah

Introduction: Cardiopulmonary bypass (CPB) with hypothermia and hemodilution increases total body water. Hemodilution most frequently causes hypothermia by increasing tissue perfusion during CPB. This is required to prevent ischemic organ damage during periods of low blood flow or circulatory arrest. MUF has another advantage over traditional ultrafiltration. The cardiopulmonary bypass has the potential to restore the contents of the CPB circuit to the patient in a concentrated form. Water retention is common in children, especially in neonates and tiny infants.

Methods: The study was conducted for 6 months from July 2020 to February 2021 at the Department of Cardiac surgery, Rawal general and dental hospital and included thirty patients (n=30) of both genders who were scheduled for pediatric heart surgery and were between the ages of 6 and12.

Results: The mean age was (6.53 ± 3.730), Height (107.63 ± 23.526), Weight (16.87 ± 5.716), Hemoglobin before (9.360 ± 1.1319) and after (11.230 ± 1.1253), Mean Volume of MUF (316.33 ± 68.405), Mean Cross Clamp Time (57.57 ± 30.458), Mean Potassium level (4.067 ± 0.3155).

Conclusion: According to the findings of our study, the use of a hemofilter increases hemoglobin and hematocrit levels when compared to pre-bypass levels, and less blood product is required for transfusion following bypass. It also has a significant impact on the control of postoperative bleeding.