Open Access Journals The Open Access Journals was founded with a mission to provide free access to scientific literature for quick dissemination of scientific updates and provide source of reference and retrieval free of cost. Research fellows and professors in various disciplines submit works in the form of manuscripts which undergo quality check before being approved for publication. Clinical Investigation Volume 10, Issue 2 A phase 1 study on midostaurin plus panobinostat in unfit acute myeloid leukemia and highrisk myelodysplastic syndrome ChinHin NG, Weiying JEN, LiangPiu KOH, Melissa OOI, Esther CHAN, MariaJannet MOGRO, Shi WANG, Jianbiao ZHOU, WeeJoo CHNG Clinical Investigation Editorial Jennifer Stewart Selectively targeting TGF with TrabedersenOT101 in treatment of evolving and mild ards in COVID19 Fatih M Uckun, Larn Hwang, Vuong Trieu Clinical impact potential of Rejuveinix RJX for prevention of fatal acute respiratory distress syndrome ARDS and multiorgan failure in COVID19 patients Fatih M Uckun, Jim Ervin, Kazim Sahin, Joy Powell, Natalie Pizzimenti, Jackie Earabino, Hendrik van Wyk, Mariette van Wyk, Peter Pacult, Taha Koray Sahin, Kristina Cabala